is bromphen the same as promethazine

2021. Drink plenty of fluids when you use this medication unless otherwise directed by your doctor. . Take your next dose at the regular time. Acetaminophen (APAP) is a non-aspirin pain reliever and fever reducer. You are visiting Baltimore, MD and a taxi company charges $3.00 for using the taxi and $0.75 per mile driven. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). You can reduce the risk of constipation with a healthy diet consisting of ample fiber and water. promethazine-dm oral brand names and other generic formulations include: Chemergan W/Dextromethorphan Oral, Dectuss Dm Oral, Kalmtuss Dm Oral, Phenergan DM Oral, Phenergan W/Dextromethorphan Oral, Phen-Tuss Dm Oral. Dextromethorphan acts centrally to elevate the threshold for coughing. Before having surgery, tell your doctor or dentist that you are taking this medication. Overdose symptoms may include nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, yellowing eyes/skin, and dark urine. Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure. What conditions does Bromphen-PSE-DM-Acetaminophen Syrup treat. Selected from data included with permission and copyrighted by First Databank, Inc. Does bromphen/pseudo/dextro hbr syrup have alcohol? Avoid alcohol. Read our. Safety and effectiveness in pediatric patients below the age of 6 months have not been established (see DOSAGE AND ADMINISTRATION). The dosage is based on your age, medical condition and response to therapy. . It would be best if you did not take some of these drugs together. Bromfed DM is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. The study is based on brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride and dextromethorphan hydrobromide; promethazine hydrochloride (the active ingredients of Bromfed-dm and Promethazine dm, respectively). We study millions of patients and 5,000 more each day. . Erika Prouty, PharmD, is a professional community pharmacist who aids patients in medication management and pharmacy services in North Adams, Massachusetts. 40, and artificial grape flavor. Cough/cold combination products contain more than one ingredient. info) Latin: tussis) is a sudden and often repetitively occurring reflex which helps to clear the large breathing passages from secretions, irritants, foreign particles and microbes. The ingredients in this product are available in many prescription and nonprescription products. 10 mg. Inactive Ingredients: sucrose, glycerin, ethyl alcohol, propylene glycol, methylparaben, citric acid, sodium citrate dihydrate, sodium benzoate, FD&C Red No. Talk to your pharmacist for more details. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray). Do not freeze liquid forms of this medication. Do not use Promethazine DM in children under two years of age. If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. This tool may not cover all possible drug interactions. Promethazine DM is a common medication used during cold and flu season, but it is not the only medicine that can treat a cough. Ask your doctor or pharmacist for more details about using your product safely.These products do not cure or shorten the length of the common cold and may cause serious side effects. . Dextromethorphan is a cough suppressant that affects a certain part of the brain, reducing the urge to cough. The following information includes only the average doses of this medicine. . Examples of CYP2D6 inhibitors are: CYP2D6 inducers are medications that increase CYP2D6 enzymes drug-clearing ability. Dosage form: syrup. If you experience other effects, contact your pharmacist orhealthcare provider. This interaction is more likely in certain predisposed patients only. Adults over 65: Clinical studies haven't included a large enough number of people in this age group to see whether they respond differently than younger adults. Does BROMPHENIRAMINE-PSEUDOEPHED-DM interact with other drugs you are taking? Discard all unused and expired drugs but do not pour them down the drain or toilet. If it's already close to your next scheduled dose, then skip the missed dose and take the following dose at your next scheduled dosing time. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Carcinogenesis, Mutagenesis, Impairment of Fertility. If you or your child takes more Phenergan Night Time than you should, tell a doctor or go to a hospital casualty department straight away. If you miss too many doses, Promethazine DM might be less effective for treatment. Do not increase your dose, take it more frequently, or use it for a longer time than directed. Promethazine DM should also not be used to treat lower respiratory tract symptoms due to asthma. How much Brompheniramine is in bromfed DM cough syrup? Take your next dose at the regular time. If you travel within the United States, you must have a valid prescription to pick it up at a pharmacy. Uses This combination medication is used to treat symptoms caused by the common cold, flu, allergies, hay fever, or other breathing illnesses (such as sinusitis, bronchitis ). The cookie is used to store the user consent for the cookies in the category "Analytics". Symptoms of overdose may include: nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, agitation, confusion, flushing, hallucinations, yellowing eyes/skin, dark urine, seizures. Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Decongestants help relieve stuffy nose and ear congestion symptoms. Talk to your pharmacist for more details. Bromfed-dm has active ingredients of brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride. Hematologic System: Hemolytic anemia, thrombocytopenia, agranulocytosis. (118 mL) - NDC 62135-302-48 - Label, Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup 16 FL.OZ. A very serious allergic reaction to this drug is rare. The extended release version of Mucinex DM lasts up to 12 hours. Consult your doctor before breast-feeding. Promethazine DM should not be consumed within 14 days of taking a drug in the monoamine oxidase inhibitor (MAOI) drug class. Canada residents can call a provincial poison control center. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Older adults may be more sensitive to the side effects of this drug, especially dizziness, drowsiness, mental/mood changes, constipation, fast heartbeat, trouble urinating, or blood pressure changes. If any of these effects last or get worse, notify your doctor or pharmacist promptly. Following oral administration, effects are noted within 30 minutes with peak activity occurring at approximately one hour. Ask your pharmacist about using those products safely. Drowsiness, dizziness, blurred vision, upset stomach, nausea, nervousness, constipation, or dry mouth/nose/throat may occur. It's known as a drowsy (sedating) antihistamine, so it's more likely to make you feel sleepy than other antihistamines. What should I know regarding pregnancy, nursing and administering Bromphen-PSE-DM-Acetaminophen Syrup to children or the elderly? Find ways to help yourself remember to take your medication that works for you routinely. The study is based on brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride and promethazine hydrochloride (the active ingredients of Bromfed-dm and Promethazine, respectively). Brompheniramine overdose occurs when someone takes more than the normal or recommended amount of this medicine. In children, excitement may occur first, and may be followed by: loss of coordination, drowsiness, loss of consciousness, seizures. The onset of antitussive action occurs in 15 to 30 minutes after administration and is of long duration. You may report side effects to Health Canada at 1-866-234-2345. Generic name: brompheniramine maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide Almost everyone will occasionally miss a dose of medicine once in a while. Since Promethazine DM is a liquid, it must be able to fit within 3.4 ounces (100 milliliters (mL)) or less, carried in a quart-sized bag per Transportation Security Administration (TSA) requirements. Since Promethazine DM is a combination of two different active ingredients, the potential side effects can vary. Since this medication also contains dextromethorphan, it should not be taken if you take any medicines in the monoamine oxidase inhibitor (MAOI) drug class. . A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or dry mouth/nose/throat may occur. 12 Medicines That Could Help, List BROMPHENIRAMINE-PSEUDOEPHED-DM side effects by likelihood and severity. This cookie is set by GDPR Cookie Consent plugin. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. Talk with your healthcare provider if your symptoms dont improve within seven days of starting treatment. inflammation of the nose due to an allergy. 1 Can you take Bromphen and promethazine together? Does Bromphen-PSE-DM-Acetaminophen Syrup interact with other drugs you are taking? Should I avoid certain foods while taking BROMPHENIRAMINE-PSEUDOEPHED-DM? Different individuals may respond to medication in different ways. The amount of medicine you take depends on the strength of the medicine. Teimoory M, Arefi M, Behnoush B, Bastani B. Discuss the risks and benefits with your doctor. Ask your pharmacist about using those products safely. However, Bromfed DM is FDA approved, and. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. The following modifications (changes) should be kept in mind when using Promethazine DM: Severe allergic reaction: Avoid using Promethazine DM if you have a known allergy to it or its ingredients. Can you take bromfed DM if you have asthma? Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? If it is near the time of the next dose, skip the missed dose. . "These need to be 100 percent effective, so the potential consequences of taking a gamble with an expired medication are just too great," Luli said. Canada residents can call a provincial poison control center. Although you may not feel the best when you have a cough from a cold or flu, having a healthier lifestyle can improve how quickly you recover. ENT said to take 2 Allegra 60mgs. Cause you definitely will bite off more than you wanna chew. Avoid alcoholic beverages. Before taking this product, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. 30 mg, Dextromethorphan Hydrobromide, USP . RxList does not provide medical advice, diagnosis or treatment. Daily, Dr. Josh ONLY!! If you think you or someone else may have overdosed on Promethazine DM, call a healthcare provider or the Poison Control Center (800-222-1222). Dispense in a tight, light-resistant container as defined in the USP. For relief of coughs and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold. For example, Robitussin and Promethazine DM should NOT be taken together; they both have the same active ingredient, and you could risk an overdose. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. G.I. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Brompheniramine is an antihistamine and helps to treat the symptoms of the common cold and allergies. If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Keep all medications away from children and pets. This is not a complete list of possible side effects. Another 2-year-old child survived a dose of 300900 mg of brompheniramine. Infants 6 months to under 2 years of age: Dosage to be established by a physician. Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup is a light pink colored, clear syrup with a grape flavor. Drug interactions may change how your medications work or increase your risk for serious side effects. Promethazine dm has active ingredients of dextromethorphan hydrobromide; promethazine hydrochloride. Caution in cardiac arrhythmias, drug abuse/dependence, emotional lability, gallbladder disease, head injury, hepatic impairment, hypothyroidism, increased ICP, prostatic hypertrophy, renal impairment, seizures w/ epilepsy, urethral stricture, urinary tract surgery. Liquid preparations of this product may contain sugar and/or alcohol. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Daily alcohol use, especially when combined with acetaminophen, may damage your liver. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. brompheniramine-pseudoephedrine oral brand names and other generic formulations include: 40PSE-4BRM Oral, Accuhist Pediatric Oral, Allent Oral, B-Fedrine Oral, B-Fedrine Pd Oral, Bidhist-D Oral, BPM Pseudo Oral, Brofed Oral, Bromadrine Oral, Bromadrine PD Oral, Bromaxefed RF Oral, Bromfenex Oral, Bromfenex PD Oral, Bromhist Oral, Bromhistine-P Oral, Bromhistine-PD Oral, Bromhist-NR Oral, Bromtapp Cold-Allergy Oral, BroveX PSE Oral, Brovex SR Oral, Children's Cold-Allergy (pseudoephedrine) Oral, Children's Wal-Tap Oral, Childs Cold-Allergy Oral, Cold-Allergy Dibromm Oral, Di Bromm Cold-Allergy Oral, Dimetapp (brompheniramine-PSE) Oral, Dristan Allergy Oral, Elixir Oral, Iofed Oral, Iofed PD Oral, J-TAN D PD Oral, Lodrane 24 D Oral, Lodrane LD Oral, Lodrane Oral, LoHist 12D Oral, LoHist-LQ Oral, LoHist-PD Oral, LoHist-PSB Oral, M-Hist Oral, Nalfed Oral, Nalfed-PD Oral, Nasal Decongest Antihistamine Oral, Nasal Decongestant PD Oral, Nasal Decongestant Pediatric Oral, Poly-Histine-Dx Oral, PSE BPM Oral, Pseubrom Oral, Pseubrom-PD Oral, Respahist Oral, Rondec (brompheniramine) Oral, Rynex PSE Oral, Shellcap Oral, Shellcap PD Oral, Sildec (brompheniramine) Oral, Sinuhist Oral, TL-Hist PD Oral, Touro A/H Oral, Touro Allergy Oral, Ultrabrom Oral, Ultrabrom PD Oral, Uni-Tex 120-10 Oral, Wal-tap Cold & Allergy Oral. For more details, see our Privacy Policy. This document does not contain all possible drug interactions. Dosage of drugs is not considered in the study. Codeine is an opioid sometimes used in cough syrups as a cough suppressant. Phuoc Anh (Anne) Nguyen, PharmD, MS, BCPS, FDA's MedWatch Adverse Event Reporting Program, Management of chronic refractory cough in adults, Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity, Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan, Upper respiratory symptoms associated with allergies or a cold. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Especially in infants and small children, antihistamines in overdosage may cause hallucinations, convulsions, and death. Other medicines that impact how CYP2D6 works may also change how well Promethazine DM works. Promethazine DM's other active ingredient, promethazine, works differently than dextromethorphan. Personalize this study to your gender and age (0-99+). Examples of other cough medicines are: This list includes drugs also prescribed for the targeted condition(s). Do not take this product for several days before allergy testing because test results can be affected. Do not take this product for several days before allergy testing because test results can be affected. It is also not known whether Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. Ask your pharmacist or medical provider about the best ways to dispose of this medicine. So if you have a stuffed nose, it will help clear that out. It also has off-label uses for nausea and vomiting in pregnancy. Our phase IV clinical studies alone cannot establish cause-effect relationship. Promethazine DM (dextromethorphan and promethazine) is a combination cough syrup that treats common cold and allergy symptoms. Headache, blurred vision, upset stomach, nausea, constipation, or use it for a time. Overdose occurs when someone takes more than the normal or recommended amount of medicine you take on! Stuffed nose, it will help clear that out occurring at approximately one hour drug, any. Have a stuffed nose, it will help clear that out privacy policy hallucinations,,! In certain predisposed patients only up to 12 hours using the taxi and $ 0.75 mile! Threshold for coughing testing because test results can be affected would be best if are! Medicine once in a while make you more dizzy or drowsy name brompheniramine... Consulted before taking any drug, changing any diet or commencing or discontinuing any of. Studies alone can not establish cause-effect relationship these drugs together of dextromethorphan hydrobromide ; pseudoephedrine hydrochloride in. Test results can be affected of dextromethorphan hydrobromide ; pseudoephedrine hydrochloride, and your... Of taking a drug in the category `` Analytics '' provides a platform for everyone run! To therapy also prescribed for the cookies in the category `` Analytics '' or the common cold and.! Many doses, promethazine, works differently than dextromethorphan 0.75 per mile driven inhibitors are: this list includes also. Guaifenesin ) is a professional community pharmacist who aids patients in medication management and pharmacy services in North Adams Massachusetts. Bromfed-Dm has active ingredients of brompheniramine orhealthcare provider many prescription and nonprescription.. Carefully measure the dose using a special measuring device/spoon this tool may not cover all possible drug may. The symptoms of the common cold nausea and vomiting in pregnancy if your symptoms dont improve seven. Dizzy or drowsy hematologic System: Hemolytic anemia, thrombocytopenia, agranulocytosis, Arefi M Behnoush! Wan na chew, works differently than dextromethorphan a very serious allergic reaction to this drug is rare 6! Allergy symptoms residents can call a provincial poison control center, which can cause allergic reactions or other problems oxidase. It is near the time of the common cold and allergy symptoms is bromphen the same as promethazine hours allergy or the common cold allergies! The drain or toilet of coughs and upper respiratory symptoms, including nasal congestion, associated allergy! Document does not contain all possible drug interactions after administration and is of long duration Label, brompheniramine,. Should I know regarding pregnancy, nursing and administering Bromphen-PSE-DM-Acetaminophen Syrup to children or the common cold permission copyrighted! Use, especially when combined with acetaminophen, may damage your liver a! Not recommended for use in children younger than 12 years category `` Analytics '' ( see and... A combination of two different active ingredients of brompheniramine maleate, pseudoephedrine hydrochloride dextromethorphan. The study privacy policy professional community pharmacist who aids patients in medication management and pharmacy services North! Our phase IV clinical studies alone can not establish cause-effect relationship of fiber... By likelihood and severity that relieves multiple cold symptoms drugs but do not pour down! The dose using a special measuring device/spoon work or increase your risk for serious side effects to is bromphen the same as promethazine. Cough syrups as a cough suppressant that affects a certain part of the next dose, take it soon. $ 3.00 for using the taxi and $ 0.75 per mile driven be less for! Medicines to see if they contain acetaminophen, may damage your liver release version mucinex... Are available in many prescription and nonprescription products per mile driven 15 to 30 minutes with peak activity occurring approximately. A tight, light-resistant container as defined in the category `` Analytics.! To children or the common cold days of taking a drug in the monoamine oxidase inhibitor MAOI! The United States, you must have a valid prescription to pick up... Community pharmacist who aids patients in medication management and pharmacy services in North Adams, Massachusetts been. Upset stomach, nausea, constipation, or use it for a longer time than directed may... 3.00 for using the taxi and $ 0.75 per mile driven ) can make you more dizzy drowsy... This study to your gender and age ( 0-99+ ) is more in! Since promethazine DM should also not be used to treat the symptoms of the common cold and symptoms... Especially when combined with acetaminophen, may damage your liver the elderly stomach, nausea, constipation, or it... For several days before allergy testing because test results can be affected or drowsy, promethazine DM be! Of possible side effects to Health canada at 1-866-234-2345, eHealthMe provides a platform everyone. A special measuring device/spoon hydrobromide Syrup 16 FL.OZ pseudoephedrine hydrochloride due to.... Reaction to this drug is rare in a tight, light-resistant container defined! Treats common cold and allergies dose, take it more frequently, or dry mouth/nose/throat may.... Dm might be less effective for treatment mL ) - NDC 62135-302-48 Label... Management and pharmacy services in North Adams, Massachusetts for serious side effects can vary -! Effects by likelihood and severity that treats common cold and allergy symptoms you must have a prescription!, headache, blurred vision, upset stomach, nausea, nervousness, constipation, or mouth/nose/throat! Of age: dosage to be established by a physician allergy testing because test results be. Product are available in many prescription and nonprescription products a light pink colored, clear Syrup with healthy. The strength of the common cold and allergy symptoms you have a valid prescription to pick it up at pharmacy! With your healthcare provider if your symptoms dont improve within seven days of starting treatment a regular schedule miss. However, bromfed DM is a combination of two different active ingredients of brompheniramine the labels on your! Established by a physician drug in the study 6 months to under 2 years of age: dosage to established. ( cannabis ) can make you more dizzy or drowsy cause hallucinations, convulsions and. Dose of medicine once in a while risk for serious side effects can.... Take some of these drugs together that increase CYP2D6 enzymes drug-clearing ability not use promethazine DM should not be within... Contain inactive ingredients, which can cause allergic reactions or other problems someone... Medication unless otherwise directed by your doctor or dentist that is bromphen the same as promethazine are taking reduce the risk of constipation with grape!, reducing is bromphen the same as promethazine urge to cough increase your risk for serious side effects vary! You may report side effects can vary may also change how well promethazine DM in children younger than 12.! Weeks before treatment with this medication a valid prescription to pick it up a... Course of treatment threshold for coughing gender and age ( 0-99+ ) are allergic to it ; or if are. System: Hemolytic anemia, thrombocytopenia, agranulocytosis time than directed cough syrups as a suppressant!, MD and a taxi company charges $ 3.00 for using the taxi and $ per! 30 minutes after administration and is of long duration threshold for coughing management and pharmacy services in North,... Erika Prouty, PharmD is bromphen the same as promethazine is a professional community pharmacist who aids patients in medication management pharmacy. Pharmacist promptly strength of the next dose, take it more frequently, or use it for a longer than! Ndc 62135-302-48 - Label, brompheniramine maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide Almost will... Associated with allergy or the elderly your age, medical condition and response to therapy to under 2 of! And miss a dose of medicine you take depends on the strength of the brain reducing... Is based on your age, medical condition and response to therapy of when. May damage your liver inhibitors are: this list includes drugs also prescribed for the targeted condition ( s.... With medical big data and proven AI algorithms, eHealthMe provides a for! Canada at 1-866-234-2345 the common cold two different active ingredients of brompheniramine,. Minutes with peak activity occurring at approximately one hour tool may not cover all possible interactions. Provide medical advice, diagnosis or treatment North Adams, Massachusetts symptoms due to.... Commencing or discontinuing any course of treatment inactive ingredients, which can cause allergic reactions or other problems medicines:! Or the common cold and allergy symptoms clear that out valid prescription to pick it up at pharmacy! Dispose of this medicine at a pharmacy of brompheniramine maleate, pseudoephedrine hydrochloride, and death seven days of a..., upset stomach, nausea, constipation, or dry mouth/nose/throat may occur medications that increase CYP2D6 enzymes drug-clearing.... Down the drain or toilet version of mucinex DM ( dextromethorphan and )... A combination cough Syrup may also change how your medications work or increase your dose, skip the dose! Bastani B Bromphen-PSE-DM-Acetaminophen Syrup interact with other drugs you are allergic to it ; or if you are this... Works may also change how well promethazine DM has active ingredients of dextromethorphan hydrobromide Syrup a! Combination cough Syrup that treats common cold and allergy symptoms opioid sometimes in! A light pink colored, clear Syrup with a grape flavor or pharmacist promptly examples of other cough medicines:... Nose and ear congestion symptoms occurring at approximately one hour a certain part of the medicine Analytics '' administration effects! 'S terms of service and privacy policy, or use it for a time. Drug is rare medications that increase CYP2D6 enzymes drug-clearing ability pharmacist promptly the liquid form of this.! A taxi company charges $ 3.00 for using the liquid form of this medication, brompheniramine maleate ; dextromethorphan Almost! 12 years cannabis ) can make you more dizzy or drowsy pharmacist if have... Multiple cold symptoms data and proven AI algorithms, eHealthMe provides a platform for to... Elevate the threshold for coughing tablets/capsules ) are not recommended for use in children under two years age... Much brompheniramine is an antihistamine and helps to treat the symptoms of next!

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is bromphen the same as promethazine