This typically happens with conventional insemination where the egg and the sperm are placed in the same culture environment for fertilization The first question is naturally, which protocol is more likely to deliver a baby, and when investigators looked at the two most popular strategies, Long Agonist and Antagonist, it became clear both were equally effective in the general IVF population. . Any 43+ Have Successful IVF with Own Egg? When do you start your next cycle? I also did ganirelix during this time. This amounts typically to a Coke vs. Pepsi kind of decision. Also covering add-ons like human growth hormone. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. As a result, the Antagonist strategy is generally preferred for women at especially high risk of developing OHSS, namely women with PCOS, younger women, women with high AMH or AFCs, African American women, and those who produced a high number of eggs in a recent cycle. This is my first time posting and was hoping for some other stories like mine. Another distinctive feature between the two protocols is that the Long Agonist protocol calls for a longer stretch of drugs to block ovulation. There are 2 - 3 core protocols: the Long Agonist, Antagonist and Flare. February 7 - lost our little twin, Baby B had no heartbeat at 20 weeks, June 8, 2011 - DD was born healthy and her twin brother was born to Heaven. I did have a decent response on the MDL and 100% fertilization with two good 5 day blasts. FET October 6, 2010 - this is it Recently went thru an IVF cycle that gave me a poor result: 3 blasts all abnormal.RE suggested BCP for 21 days followed by lupron. IVF #2, we did estrogen priming, Follistim, Menopur, Tev Tropin (human growth hormone), Cetrotide. I cannot say if it will be a success yet, as I am currently doing the EPP protocol. Thanks! More than I wanted, I think! 6 responded, 5 retrieved, 3 fertilized normally, put all 3 back in at 3dpt - I am currently 27 weeks with one baby girl. Weill Cornell Medical Center, Division Chief I am about to embark on my IVF#6 cycle (1st time at CCRM)- I've always done OCP/BCP before my IVF stim cycle(antagonist) and have produced between 15-19 eggs each time. For my cycle in July they are not giving me Lupron but are giving me Antagon. So I think I was on estrogen for about a couple weeks then started stimming (antagonist protocol). If ok, then start stimulation The many repeat bloodworks & ultrasoundsLast stimulation shot + triggerRetrievalSo I started my process in the mid-September and my retrieval happened in early NovemberAlso, I was on MicroFlare protocol, so I am not sure what other medications you might be taking. So it seems to me it's time to change the protocol, do another cycle and gather more inform, I am 36 years old. I think you both are at Cornell (were) with this estrogen priming protocol will you try again with them, and request not to do estrogen priming? Yes, we did the same thing. He is starting me on a peculiar Omnitrope protocol as well:- he wants me mixing two vials of omnitrope in 10 mL of water and inject myself with 1 mL daily until egg retrievaland to keep refilling the Rx until retrieval. Hottest Topics -- Last 30 Days Was wondering since your AMH was good and FSH, why did they recommend the Estrogen priming protocol for you? First, make sure your seeds are dry before sending them in. I have been doing some research and reading and I was reading that for older patients, a different protocol where less meds are used is usually recommend. My first aIVF cycle was cx'd , due to poor/slow response and was probably due to the Birth control pills and lupron. I think the stims usually last longer with EPP, but my quality was much better. EPP results: 17 retrieved, 13 mature, 8 fertilized with PICSI, 2 hatching blasts on day 6 have been biopised. Comparing protocol A and B, there were no significant difference between embryologic data, however there were slight . No BCP - started my period, did cycle day 2 testing FSH was good (I had high a FSH of 15 so EPP helped that) then started meds. Babies due June 26, 2011 Many REs swear by this for DOR. I wound up with 5 fertilized embryos; transferred two grade A on day 3--got my now 2yo daughter. MENTS: This time around I did estrogen priming and the results of my day 5 ultrasound were disappointing (8 follicles, with an E2 level of 98.6) and now at day 7 they are worse (2 of the smaller follicles haven't budged in size so only 6 seem to be in the game but 3 are leading). 05/18/2018 23:18 Subject : Protocol . Below you can see that when investigators gave poor responders 450 IUs or 150 IUs per day, the groups had nearly identical success rates. Yea, sometimes the smallest of tweaks can make such a big difference. Estrogen priming is usually matched with an antagonist to prevent ovulation. I felt icky too the first day of starting estrace but I think it's also because they put me on a zpac to kill any infections and that made me sick my fingers are crossed that your period doesn't come and you can start cycling. Second, this study was only done in cycles using a fresh transfer. The stim phase was just like a usual antagonist cycle. Omnitrope/HGH pricing and protocol question? poor responders or women with PCOS). it's 1 week since last patch. I am planning on doing 2-3 cycles with banking and then CCS testing due to previous miscarriages. They did mature the next day, and they tried to fertilize them, but they did not. Have questions about navigating your Inspire support community or need assistance from one of our Inspire Moderators? Anyone with very low AMH do the estrogen priming and have a good response? Froze 3. Patients undergoing a MFP required more injections (40 vs. 26) than an EPP and spent an average of $4,375.00 compared to EPP patients who spent $5,485.00. They studied what happens when you replace gonadotropin with clomid (a cheaper, less potent alternative) for a few days before the retrieval. Gonal f 225, menopur 75. ET oct 2nd - 2 embryos transferred Had two follicles but one disappeared day of egg retrieval. 9 Over the next several days you will have ultrasound and blood tests periodically and given instructions on the dosage of FSH to take Usually first Many customers have had positive experiences ordering from them, and their customer service has been praised for keeping buyers updated on order status. You are posting as a Guest without being logged in. In the case of the fresh transfers, you can clearly see a similar effect to what investigators found above: success rates drop with more drug. 2 Girls!! I just had my first IVF and it was unsuccesful. Lupron when take in larger doses suppresses pituitary function, but when taken in smaller doses, it does the opposite. Will let you know how things go from here. Thanks for sharing your story. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. Confirmed. Estrogen Priming is completely different, so therefore without birth control pill.I would ask your doctor, but I guess you just do nothing while preparing for the cycle. Hence we see mini-IVF protocols used at places like New Hope Fertility in NYC (http://www.newhopefertility.com/?topic=minimal-stimulation-mini-ivf) and the Infertility Center of St Louis (http://www.infertile.com/closlook/biograph.htm); and, Hello, The dr decided to put a halt to the process for that month. I just had my ER last week: stimmed for 13 days, started ganerilix on stim day 8, retreived 7 eggs, 3 were mature, 3 fertilized, 1 blastocyst was frozen today on day 5 and I have 2 morulas that will bhopefully be frozen tomorrow as long as they are blastocysts. I wound up with 5 fertilized embryos; transferred two grade A on day 3--got my now 2yo daughter. This protocol is used almost exclusively in women whove had a poor response in a previous cycle or who have evidence of diminished ovarian reserve (AMH less than 0.5 or an AFC less than 5). In the next section well walk you through the mechanics of each protocol. I imagine the Follistim is lowered partly to keep the egg number from increasing (had OHSS w/IVF #1). Associate Director, REI I am scheduled to take estrace 7 days after ovulation coming up (the cycle before) presumably for about 7 days until next cycle Not sure why you would do prometrium before you cycle? Below is a meta-analysis of 17 (relatively small) studies that, taken together, show the strategies have nearly identical pregnancy rates. I started my estrace this morning and feel a little icky so far. No, IVF 5 was the estrogen priming. Has anyone with failed IVF stim tried mini/micro IVF? Hey Michelle, I haven't forgotten about you. Cool.let me know what he says if you would please. Hi @cmugnolo, you have a similar situation to mine perhaps. They are generally used for suppression in Long Lupron Protocols. So I think I was on estrogen for about a couple weeks then started stimming (antagonist protocol). Estrogen Priming Protocol: For some women, especially for those who have diminished ovarian reserve, it becomes necessary to help the response to the Antagonist protocol. The misoprostol was not expensive; on average, it's about $30. The reality is the data is sparse for most adjuvants and even amongst those with the most credible data, the quality of the trials have been fairly underwhelming. Was one of my worst cycles. Until then, its hard to make a definitive call on whether these drugs work. One of the most important steps in the in vitro fertilization is stimulating the ovaries to develop multiple eggs. How does a micro-flare protocol differ from mini IVF vs natural cycle? What To Do When PGT-A & Grading Results Conflict? We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. Privacy Policy - DS was born June 22nd, 2007!!!!! After 2 years, tons of tests and 5 IVF cycles, it still feels unreal.Estrogen Priming protocol does not have birth control pills. I have hypothalamic anvolution, DH normal. There are a number of drugs that can be tacked onto the beginning of a cycle that may increase the odds of success. We have been TTC 14 months, but diagnosed at 6 months so did injectables and TI for 3 cycles without bp, although my follicles responded well. I just had an appointment with an RE who told me that because of my high FSH levels there is low probability of me being able to get pregnant, but he also said that he could not do IVF or I could not take any fertility drugs because it would only be mimicking what my body is already trying to do and that is not even working. Right ovary has 2-4 follies<12mm. I stimmed for 13 days. I'll keep my fingers crossed for you as I see you just did an IUI. Estrogen priming is a protocol used during in vitro fertilization (IVF) to facilitate a more gradual and coordinated growth of follicles in the ovary in women with diminished ovarian reserve (DOR). I am curious what anyone's experience has been with EPP. However, when it comes to specific IVF populations, its clear that certain strategies and doses are better than others. I used two patches a dayandchanged the patches every third day. Hi there. The deadline for sending in seeds was October 15th, but there are still plenty of ways to get involved. Antagonist cycle you have a good response then CCS testing due to poor/slow response and hoping! Are posting as a Guest without being logged in aIVF cycle was cx 'd, due to previous.... Of egg retrieval is lowered partly to keep the egg number from increasing ( OHSS! 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